HawgGoneIt Posted March 26, 2020 Report Share Posted March 26, 2020 12 minutes ago, The Guru said: It's educating people so they know that those in charge are incompetent and irresponsible boobs who don't believe in preparation or procedure or any of that other silly stuff. Putting morons in charge has consequences. The only people out there that are actually prepared at this point are the one's smart enough to know that the administration is full of shit. Quote Link to comment Share on other sites More sharing options...
BUFORDGAWOLVES Posted March 26, 2020 Report Share Posted March 26, 2020 https://www.politico.com/news/2020/03/25/trump-coronavirus-national-security-council-149285 Playbook is in the link.... BGW Quote Link to comment Share on other sites More sharing options...
BUFORDGAWOLVES Posted March 26, 2020 Report Share Posted March 26, 2020 Science Daily's report on the origin... The novel SARS-CoV-2 coronavirus that emerged in the city of Wuhan, China, last year and has since caused a large scale COVID-19 epidemic and spread to more than 70 other countries is the product of natural evolution, according to findings published today in the journal Nature Medicine. The analysis of public genome sequence data from SARS-CoV-2 and related viruses found no evidence that the virus was made in a laboratory or otherwise engineered. "By comparing the available genome sequence data for known coronavirus strains, we can firmly determine that SARS-CoV-2 originated through natural processes," said Kristian Andersen, PhD, an associate professor of immunology and microbiology at Scripps Research and corresponding author on the paper. In addition to Andersen, authors on the paper, "The proximal origin of SARS-CoV-2," include Robert F. Garry, of Tulane University; Edward Holmes, of the University of Sydney; Andrew Rambaut, of University of Edinburgh; W. Ian Lipkin, of Columbia University. Coronaviruses are a large family of viruses that can cause illnesses ranging widely in severity. The first known severe illness caused by a coronavirus emerged with the 2003 Severe Acute Respiratory Syndrome (SARS) epidemic in China. A second outbreak of severe illness began in 2012 in Saudi Arabia with the Middle East Respiratory Syndrome (MERS). On December 31 of last year, Chinese authorities alerted the World Health Organization of an outbreak of a novel strain of coronavirus causing severe illness, which was subsequently named SARS-CoV-2. As of February 20, 2020, nearly 167,500 COVID-19 cases have been documented, although many more mild cases have likely gone undiagnosed. The virus has killed over 6,600 people. Shortly after the epidemic began, Chinese scientists sequenced the genome of SARS-CoV-2 and made the data available to researchers worldwide. The resulting genomic sequence data has shown that Chinese authorities rapidly detected the epidemic and that the number of COVID-19 cases have been increasing because of human to human transmission after a single introduction into the human population. Andersen and collaborators at several other research institutions used this sequencing data to explore the origins and evolution of SARS-CoV-2 by focusing in on several tell-tale features of the virus. The scientists analyzed the genetic template for spike proteins, armatures on the outside of the virus that it uses to grab and penetrate the outer walls of human and animal cells. More specifically, they focused on two important features of the spike protein: the receptor-binding domain (RBD), a kind of grappling hook that grips onto host cells, and the cleavage site, a molecular can opener that allows the virus to crack open and enter host cells. Evidence for natural evolution The scientists found that the RBD portion of the SARS-CoV-2 spike proteins had evolved to effectively target a molecular feature on the outside of human cells called ACE2, a receptor involved in regulating blood pressure. The SARS-CoV-2 spike protein was so effective at binding the human cells, in fact, that the scientists concluded it was the result of natural selection and not the product of genetic engineering. This evidence for natural evolution was supported by data on SARS-CoV-2's backbone -- its overall molecular structure. If someone were seeking to engineer a new coronavirus as a pathogen, they would have constructed it from the backbone of a virus known to cause illness. But the scientists found that the SARS-CoV-2 backbone differed substantially from those of already known coronaviruses and mostly resembled related viruses found in bats and pangolins. "These two features of the virus, the mutations in the RBD portion of the spike protein and its distinct backbone, rules out laboratory manipulation as a potential origin for SARS-CoV-2" said Andersen. Josie Golding, PhD, epidemics lead at UK-based Wellcome Trust, said the findings by Andersen and his colleagues are "crucially important to bring an evidence-based view to the rumors that have been circulating about the origins of the virus (SARS-CoV-2) causing COVID-19." "They conclude that the virus is the product of natural evolution," Goulding adds, "ending any speculation about deliberate genetic engineering." Possible origins of the virus Based on their genomic sequencing analysis, Andersen and his collaborators concluded that the most likely origins for SARS-CoV-2 followed one of two possible scenarios. In one scenario, the virus evolved to its current pathogenic state through natural selection in a non-human host and then jumped to humans. This is how previous coronavirus outbreaks have emerged, with humans contracting the virus after direct exposure to civets (SARS) and camels (MERS). The researchers proposed bats as the most likely reservoir for SARS-CoV-2 as it is very similar to a bat coronavirus. There are no documented cases of direct bat-human transmission, however, suggesting that an intermediate host was likely involved between bats and humans. In this scenario, both of the distinctive features of SARS-CoV-2's spike protein -- the RBD portion that binds to cells and the cleavage site that opens the virus up -- would have evolved to their current state prior to entering humans. In this case, the current epidemic would probably have emerged rapidly as soon as humans were infected, as the virus would have already evolved the features that make it pathogenic and able to spread between people. In the other proposed scenario, a non-pathogenic version of the virus jumped from an animal host into humans and then evolved to its current pathogenic state within the human population. For instance, some coronaviruses from pangolins, armadillo-like mammals found in Asia and Africa, have an RBD structure very similar to that of SARS-CoV-2. A coronavirus from a pangolin could possibly have been transmitted to a human, either directly or through an intermediary host such as civets or ferrets. Then the other distinct spike protein characteristic of SARS-CoV-2, the cleavage site, could have evolved within a human host, possibly via limited undetected circulation in the human population prior to the beginning of the epidemic. The researchers found that the SARS-CoV-2 cleavage site, appears similar to the cleavage sites of strains of bird flu that has been shown to transmit easily between people. SARS-CoV-2 could have evolved such a virulent cleavage site in human cells and soon kicked off the current epidemic, as the coronavirus would possibly have become far more capable of spreading between people. Study co-author Andrew Rambaut cautioned that it is difficult if not impossible to know at this point which of the scenarios is most likely. If the SARS-CoV-2 entered humans in its current pathogenic form from an animal source, it raises the probability of future outbreaks, as the illness-causing strain of the virus could still be circulating in the animal population and might once again jump into humans. The chances are lower of a non-pathogenic coronavirus entering the human population and then evolving properties similar to SARS-CoV-2. BGW Quote Link to comment Share on other sites More sharing options...
15yds4gibberish Posted March 26, 2020 Report Share Posted March 26, 2020 1 hour ago, The Guru said: The shit is the virus. The response is how we're dealing with it. We're criticizing the response. And here is why it is important to criticize the response. IMPOTUS tweeted this yesterday. Meanwhile Fauci said this yesterday: “You don’t make the timeline. The virus makes the timeline...You have got to go with what the situation on the ground is... you need the data." Let's not send workers out to own the libs until we have the data to safely do so. Quote Link to comment Share on other sites More sharing options...
thc6795 Posted March 26, 2020 Report Share Posted March 26, 2020 11 minutes ago, 15yds4gibberish said: And here is why it is important to criticize the response. IMPOTUS tweeted this yesterday. Meanwhile Fauci said this yesterday: “You don’t make the timeline. The virus makes the timeline...You have got to go with what the situation on the ground is... you need the data." Let's not send workers out to own the libs until we have the data to safely do so. he also said the President was very flexible on his Easter timeline and was listening to ALL of his advisors. Of course you left that out. 1 1 Quote Link to comment Share on other sites More sharing options...
DBP66 Posted March 26, 2020 Report Share Posted March 26, 2020 10 minutes ago, thc6795 said: he also said the President was very flexible on his Easter timeline and was listening to ALL of his advisors. Of course you left that out. all his advisors huh Tex??...LOL..first he'll talk to the ones who are worried about the economy...then the ones that are worried about his re-election...then the ones who know what their talking about..the Dr.'s... and like he said himself he's more worried about the election than people's health..."in the hope that it will be detrimental to my election success"....well at least he has his priorities right huh Tex?... 1 Quote Link to comment Share on other sites More sharing options...
thc6795 Posted March 26, 2020 Report Share Posted March 26, 2020 1 minute ago, DBP66 said: all his advisors huh Tex??...LOL..first he'll talk to the ones who are worried about the economy...then the ones that are worried about his re-election...then the ones who know what their talking about..the Dr.'s... and like he said himself he's more worried about the election than people health..."in the hope that it will be detrimental to my election success"....well at least he has his priorities right huh Tex?... When did he say he was worried about the election you fucking worm? You're really a piss ant. Your dad should be executed for treason. 1 Quote Link to comment Share on other sites More sharing options...
DBP66 Posted March 26, 2020 Report Share Posted March 26, 2020 2 minutes ago, thc6795 said: When did he say he was worried about the election you fucking worm? You're really a piss ant. Your dad should be executed for treason. "The LameStream Media is the dominant force in trying to get me to keep our Country closed as long as possible in the hope that it will be detrimental to my election success"...YESTERDAY..…. Quote Link to comment Share on other sites More sharing options...
thc6795 Posted March 26, 2020 Report Share Posted March 26, 2020 1 minute ago, DBP66 said: "The LameStream Media is the dominant force in trying to get me to keep our Country closed as long as possible in the hope that it will be detrimental to my election success"...YESTERDAY..…. You are too fucking stupid 1 Quote Link to comment Share on other sites More sharing options...
The Guru Posted March 26, 2020 Report Share Posted March 26, 2020 30 minutes ago, thc6795 said: You are too fucking stupid *When a dumb person realizes that he was wrong but isn't smart or clever enough to respond in any other way* 1 Quote Link to comment Share on other sites More sharing options...
The Guru Posted March 26, 2020 Report Share Posted March 26, 2020 I'm sure the leader of the Federal Government has no responsibility for this either. If you think he does, then you're pointing the finger! Job Vacancies and Inexperience Mar Federal Response to Coronavirus Quote Link to comment Share on other sites More sharing options...
maxchoboian Posted March 26, 2020 Report Share Posted March 26, 2020 1 hour ago, 15yds4gibberish said: And here is why it is important to criticize the response. IMPOTUS tweeted this yesterday. Meanwhile Fauci said this yesterday: “You don’t make the timeline. The virus makes the timeline...You have got to go with what the situation on the ground is... you need the data." Let's not send workers out to own the libs until we have the data to safely do so. LameStream Media. The guy is 70-something years old and uses terms like this. Weird. 5th grade weird. It's like kids talking at recess or lunch and trying to be funnier than one another. "You like to eat at Booger King", "Oh yeah, at least I don't have dinner every night at Walfart" The President. Who on here will admit they enjoy when he decides to, adolescent-like, mess with the names of things? 2 2 Quote Link to comment Share on other sites More sharing options...
15yds4gibberish Posted March 26, 2020 Report Share Posted March 26, 2020 2 hours ago, maxchoboian said: LameStream Media. The guy is 70-something years old and uses terms like this. Weird. 5th grade weird. It's like kids talking at recess or lunch and trying to be funnier than one another. "You like to eat at Booger King", "Oh yeah, at least I don't have dinner every night at Walfart" The President. Who on here will admit they enjoy when he decides to, adolescent-like, mess with the names of things? @maxchoboian This is a good post. With a wide latitude for actual humor, whenever I encounter an adult that speaks, writes, and acts like a schoolyard adolescent (among other things), I'm filled with this deep and abiding sense that something went terribly wrong along the way... Counterfactual's rarely convince anybody, and business and politics are not really all that much alike, but I'm convinced that if IMPOTUS were CEO of a Fortune 500, behaving the way he does, the board would have removed him long ago. 2 Quote Link to comment Share on other sites More sharing options...
I AM IRONMAN Posted March 26, 2020 Report Share Posted March 26, 2020 7 hours ago, RedZone said: Nurses having to wear trash bags on the front line in New York is absolutely unacceptable....... All this country cares about is the stock market and sinking billions and billions of dollars into the military. I don't think the USA would send the ARMY to the front lines in trash bags. Disgraceful This country sucks really.... Then leave...ass wipe 1 Quote Link to comment Share on other sites More sharing options...
The Guru Posted March 26, 2020 Report Share Posted March 26, 2020 3 hours ago, maxchoboian said: Who on here will admit they enjoy when he decides to, adolescent-like, mess with the names of things? @thc6795 @Blueliner @GardenStateBaller Quote Link to comment Share on other sites More sharing options...
I AM IRONMAN Posted March 26, 2020 Report Share Posted March 26, 2020 Krusty the emotionally upset and confused strikes again NR is tough...LOL😂😂😂 1 Quote Link to comment Share on other sites More sharing options...
DBP66 Posted March 26, 2020 Report Share Posted March 26, 2020 ^^ the flying Dutchmams are much tougher!!..LOL....🤡 Quote Link to comment Share on other sites More sharing options...
maxchoboian Posted March 26, 2020 Report Share Posted March 26, 2020 15 minutes ago, 15yds4gibberish said: @maxchoboian This is a good post. With a wide latitude for actual humor, whenever I encounter an adult that speaks, writes, and acts like a schoolyard adolescent (among other things), I'm filled with this deep and abiding sense that something went terribly wrong along the way... Counterfactual's rarely convince anybody, and business and politics are not really all that much alike, but I'm convinced that if IMPOTUS were CEO of a Fortune 500, behaving the way he does, the board would have removed him long ago. He won the election, and his behavior was not dissimilar during the campaign. I can call it a 5th grade election all I want, but he won. Your point on the CEOs is interesting. I agree, and can't imagine a CEO of a Fortune 500 carrying on like him. There are some Steve Jobs guys out there who tend to be assholes, but not adolescent assholes. The adolescent part is what's weird. Speaking of Jobs, I also worked with Tim "Apple" long before he took over at Apple. He was a sharp guy, but I was not too close to him (I'm no C-level veteran). 2 Quote Link to comment Share on other sites More sharing options...
The Guru Posted March 26, 2020 Report Share Posted March 26, 2020 3 hours ago, maxchoboian said: Who on here will admit they enjoy when he decides to, adolescent-like, mess with the names of things? Oops. I forgot one. @I AM IRONMAN 1 Quote Link to comment Share on other sites More sharing options...
HawgGoneIt Posted March 26, 2020 Report Share Posted March 26, 2020 What I know, is, Phoebe Puntney Hospital in Albany lost four more people today, have just announced they have over 200 confirmed cases, I think last mention was 217. They have 4 beds open at this point and they aren't ICU beds. The people that were in those beds moved to ICU beds because the others that died opened those up. The markets are shot though. That seems very important to some doctors for some reason. 1 Quote Link to comment Share on other sites More sharing options...
DBP66 Posted March 26, 2020 Report Share Posted March 26, 2020 Just now, The Guru said: Oops. I forgot one. @I AM IRONMAN the biggest clown on here!...🤡 Quote Link to comment Share on other sites More sharing options...
maxchoboian Posted March 26, 2020 Report Share Posted March 26, 2020 1 minute ago, HawgGoneIt said: What I know, is, Phoebe Puntney Hospital in Albany lost four more people today, have just announced they have over 200 confirmed cases, I think last mention was 217. They have 4 beds open at this point and they aren't ICU beds. The people that were in those beds moved to ICU beds because the others that died opened those up. The markets are shot though. That seems very important to some doctors for some reason. Strange what's going on in your area. Not pleasant. How many died of the common flu in Phoebe Puntney Hospital today? Surely, many more than 4. Quote Link to comment Share on other sites More sharing options...
concha Posted March 26, 2020 Report Share Posted March 26, 2020 3 hours ago, maxchoboian said: Who on here will admit they enjoy when he decides to, adolescent-like, mess with the names of things? I thought it was funnier when the libs do stuff like call illegal immigrants "undocumented immigrants" (like someone just forgot to hand them a visa while they swam across the river) and terrorist acts are "man-caused disasters". 1 Quote Link to comment Share on other sites More sharing options...
The Guru Posted March 26, 2020 Report Share Posted March 26, 2020 8 minutes ago, concha said: I thought it was funnier when the libs do stuff like call illegal immigrants "undocumented immigrants" (like someone just forgot to hand them a visa while they swam across the river) and terrorist acts are "man-caused disasters". What. A. Clown. 🤡 Quote Link to comment Share on other sites More sharing options...
concha Posted March 26, 2020 Report Share Posted March 26, 2020 1 minute ago, The Guru said: What. A. Clown. 🤡 Andy! Quick! What's a bigger number 1.3? Or.. 1.2? Andy always gets this wrong. 🤣 Quote Link to comment Share on other sites More sharing options...
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